Publications

Journal Articles



  1. S. R. Ayakar, S. V. Pawar, K. Ievdokymenko, S. Hallam & V. G. Yadav, "A new model for control of metabolic flux within the non-mevalonate pathway", in preparation

  2. I. L. Co, N. T. Lo, R. Ghaemi, A. Kritharis, S. McGrath, K. Sakaki & V. G. Yadav, "Elucidating the link between traumatic force, neural tissue deformation and tau aggregation", in preparation

  3. G. Subedi, S. K. Srivastava, F. Tao, H. Trajano & V. G. Yadav, "Total atom utilization of mireal ores using biohydrometallurgical processing", in preparation

  4. G. Subedi, N. Mora & V. G. Yadav, "Consortial dynamics of bioleaching", in preparation

  5. P. Chegounian, D. Goertsen & V. G. Yadav, "A kill switch for biocontainment of in situ naphthenic acid degrading cultures", in preparation

  6. D. Goertsen, P. Chegounian & V. G. Yadav, "Transcriptomic and metabolomic profiling of naphthenic acid degrading consortia", in preparation

  7. M. Kabiri, I. L. Co, P. Roy, S. Pawar, S. K. Srivastava, A. Kritharis, S. H. Kamal, U. Kumar, S. Hossain & V. G. Yadav, "Medicine-by-design: Discovery & development of a novel therapy for Epidermolysis Bullosa Simplex", submitted

  8. R. Ghaemi & V. G. Yadav, "Organs-to-go: What is preventing engineered tissues from becoming mainstream medical products", submitted

  9. A. Sharan, D. Goertsen, S. Hallam and V. G. Yadav, “The circular bioeconomy: Achieving sustainability through design”, under revision

  10. A. Raghavan & V. G. Yadav, “Medicine-by-design”, under revision

  11. V. G. Yadav, S. Pathankar, A. Jeswani, S. Renneckar & G. D. Yadav, “The path forward for biomass valorization”, under revision

  12. S. Pathankar, S. Ayakar, S. Renneckar & V. G. Yadav, "The V-Factor: Augmenting the E-Factor for a more complete technoeconomic assessment of chemical processes", accepted, Bioproducts Business (2018)

  13. R. Ghaemi, I. Co, M. McFee & V. G. Yadav, "Brain organoids: A new, transformative research tool for neuroscience", accepted, Advanced BioSystems (2018)

  14. S. Pawar, S. Hallam & V. G. Yadav, "Metagenomic discovery of a novel transaminase for valorization of monoaromatic compounds", RSC Advances, 8, 22490-22497 (2018)

  15. S. K. Srivastava, P. Piwek, S. Ayakar & V. G. Yadav, "A biogenic photovoltaic material", Small, 14(26), 1800729 (2018)

  16. D. Korvin & V. G. Yadav, "A molecular switch that enhances productivity of bioprocesses by bridging metabolic and macroscopic process control", Molecular Systems Design & Engineering, 3, 550-559 (2018)

  17. M. Kabiri, S. H. Kamal, S. V. Pawar, S. Hatzikiriakos, U. Kumar, S. Hossain & V. G. Yadav, "A stimulus-responsive, nanoparticle-laden polymeric formulation for ocular drug delivery", Drug Delivery & Translational Research, 8(3), 484-495 (2018)

  18. S. K. Srivastava & V. G. Yadav, "Bionic manufacturing: Towards cyborg cells and sentient microbots", Trends in Biotechnology, 36(5), 483-487 (2018)

  19. J. C. H. Ho, S. V. Pawar, S. J. Hallam & V. G. Yadav, "An improved whole-cell biosensor for the discovery of lignin-transforming enzymes in functional metagenomic screens", ACS Synthetic Biology, 7(2), 392-398 (2018)

  20. J. Varela, F. Lammoglia, S. V. Pawar & V. G. Yadav, "Cheminformatic analysis of anti-malarial chemical space illuminates therapeutic mechanisms and offers strategies for therapy development", advanced online publication, Journal of Chemical Information & Modeling, 57(9), 2119-2131 (2017)

  21. C. L. Bayly & V. G. Yadav, "Towards precision engineering of canonical polyketide synthase domains: Recent advances and future prospects", Molecules, 22(2), 235 (2017)

  22. S. V. Pawar, J. C. H. Ho, G. D. Yadav & V. G. Yadav, "The impending renaissance in discovery & development of natural products", Current Topics in Medicinal Chemistry, 17(2), 251-267 (2017)

  23. V. G. Yadav, "The rebirth of manufacturing?", The Medicine Maker, 1(4), 23-29 (2015)

  24. V. G. Yadav, "Unraveling the multispecificity and catalytic promiscuity of taxadiene monooxygenase", Journal of Molecular Catalysis B: Enzymatic, 110, 154-164 (2014)

  25. V. G. Yadav, "Biosynthonics: Charting the future role of biocatalysis & metabolic engineering in drug discovery", Industrial & Engineering Chemistry Research, 53(49), 18597-18610 (2014)

  26. V. G. Yadav & G. Stephanopoulos, "Microbial metabolic engineering: The ultimate paradigm for continuous pharmaceutical manufacturing", ChemSusChem, 7(7), 1847-1853 (2014)

  27. V. G. Yadav, "Combining metabolic pathway design and retrosynthetic planning for the design of a novel semisynthetic manufacturing scheme for paclitaxel", Organic Process Research & Development, 18(6), 816-826 (2014)

  28. V. G. Yadav, "Winning the drug lottery", The Biochemist, 34(4), 32-35 (2012)

  29. V. G. Yadav*, M. de Mey*, C. G. Lim, P. K. Ajikumar & G. Stephanopoulos, "The future of metabolic engineering & synthetic biology: Towards a systematic practice", Metabolic Engineering, 14(3), 233-241 (2012)

  30. V. G. Yadav & G. Stephanopoulos, "Reevaluating synthesis by biology", Current Opinion in Microbiology, 13(3), 371-376 (2010)

  31. V. G. Yadav & G. D. Yadav, "Fuelling the Indian economic engine by retooling Indian tech education", Current Science, 98(11), 1442-1457 (2010)

  32. V. G. Yadav & G. D. Yadav, "Education in a developing world", The Chemical Engineer, 11, 30-32 (2010)

  33. T. Y. Chang*, V. G. Yadav*, S. de Leo, A. Mohedas, B. Rajalingam, S. Selvarasah, M. Dokmeci & A. Khademhosseini, "Cell & protein compatibility of parylene-C surfaces" Langmuir, 23(23), 11718-11725 (2007)

  34. C. Rivest, D. W. G. Morrison, J. Rubin, B. Ni, V. G. Yadav, A. Mahdavi, J. M. Karp & A. Khademhosseini, "Microscale hydrogels: Fabrication, applications and mechanical properties", Journal of Mechanics of Materials and Structures, 2(6), 1103-1119 (2007)


Books



  1. V. G. Yadav, "Biosynthonics For Drug Discovery", Taylor & Francis, in preparation

  2. V. G. Yadav & G. D. Yadav (co-editors), "Organocatalysis in the Fine & Specialty Chemicals Industry", Taylor & Francis, in preparation


Book Chapters



  1. D. Klein-Marcushamer*, V. G. Yadav*, A. Ghaderi & G. Stephanopoulos, "De novo metabolic engineering and the promise of synthetic DNA" in Biosystems Engineering I: Creating Superior Biocatalysts, part of the Advances in Biotechnology/Biochemical Engineering Series, edited by Christoph Wittmann & Rainer Krull (2010)

  2. V. G. Yadav, M. Brigham, C. Rivest, Y. Ling, D. Wright & A. Khademhosseini, "Micro- and nanoscale technologies in high-throughput biomedical experimentation" in NanoScience in Biomedicine, edited by Donglu Shi (2009)


Invited Talks and Public Lectures



  1. V. G. Yadav, "Medicine-by-design: Developing a cure for Epidermolysis Bullosa Simplex", Emerging Leader of Chemical Engineering Distinguished Lecture, 67th Annual Conference of the Canadian Society for Chemical Engineering, Edmonton, AB (October 2017)

  2. V. G. Yadav, "Solving problems in medicine using chemical engineering", Distinguished Seminar Series, Department of Chemical Engineering, University of Waterloo, Waterloo, ON (July 2017)

  3. V. G. Yadav, "Solving grand problems using synthetic biology", Plenary Lecture & Panel Member, World Congress of Industrial Biotechnology, Montreal, QC (July 2017)

  4. V. G. Yadav, "Building brains to fight Alzheimer's disease", Distinguished Seminar Series, Department of Chemical Engineering, City College of the City University of New York, New York, USA (May 2017)

  5. V. G. Yadav, "Building brains to fight Alzheimer's disease", BC Regenerative Medicine Symposium, Vancouver, BC (May 2017)

  6. V. G. Yadav, "Neuroengineering & organ bioprinting", International Roundtable on Printing the Future of Therapeutics in 3D, Vancouver, BC (May 2017)

  7. V. G. Yadav, "Building brains to fight Alzheimer's disease", Distinguished Seminar Series, Department of Chemical Engineering, City College of the City University of New York, New York, USA (May 2017)

  8. V. G. Yadav, "From biofuels to brains: How bioengineering will save the world", G. M. Abhyankar Distinguished Lectureship, Institute of Chemical Technology, Mumbai, India (December 2016)

  9. V. G. Yadav, "Synthetic biology and climate change", Genome British Columbia's Bring Genomics Home Public Lecture Series, Vancouver, BC (November 2016)

  10. V. G. Yadav, "BC's bioeconomy and its role in mitigating the adverse effects of climate change", Genome British Columbia Climate Change Workshop, Vancouver, BC (September 2016)

  11. V. G. Yadav, "A vision for the future bioeconomy', EMN Bioresource Conference 2016, Budapest, Hungary (September 2016)

  12. V. G. Yadav, "How to build a brain?", Peter Wall Institute for Advanced Studies, Vancouver, BC (January 20, 2016)

  13. V. G. Yadav, "Biosynthonics: Charting the future role of biocatalysis & metabolic engineering in drug discovery", invited talk, 19th Annual ACS Green Chemistry & Engineering Conference, Washington, DC (July 2015)

  14. V. G. Yadav, "Biosynthetic engineering for the assembly of superior drugs", Annual Congress of the Indian Institute of Chemical Engineers, Mumbai, India (2013)

  15. V. G. Yadav, P. K. Ajikumar & G. Stephanopoulos, "A new vision for pharming", MIT-ILP Systems Biology Conference, Cambridge, MA (2011)


Oral Presentations



  1. V. G. Yadav, "Building brains to fight Alzheimer's disease", World Congress of Chemical Engineering, Barcelona, Spain (October 2017)

  2. V. G. Yadav, "The path forward for biomass valorization", World Congress of Chemical Engineering, Barcelona, Spain (October 2017)

  3. V. G. Yadav, "Biosynthonics: Revving the engine of biology to unleash the power of green chemistry", 65th Canadian Society of Chemical Engineering Conference, Calgary, AB (October 2015)

  4. S. Pawar, J. C. H. Ho, C. Strachan, S. Hallam & V. G. Yadav, "Biosensor development for metagenomic profiling of lignin transforming biocatalysts", 5th International Conference on Biorefining, Vancouver, BC (August 2015)

  5. V. G. Yadav, "Biosynthonics: Revving the engine of biology to unleash the power of green chemistry", 65th Canadian Society of Chemical Engineering Conference, Calgary, AB (October 2015)

  6. V. G. Yadav, P. K. Ajikumar, C. G. Lim & G. Stephanopoulos, "Systems biotechnology for drug discovery & development", Advances in Biotechnology Product Development session, 243rd American Chemical Society National Meeting & Exposition, San Diego, CA (2012)

  7. V. G. Yadav & G. Stephanopoulos, "Metabolic engineering for taxol biosynthesis in microbial hosts", Chemical and Pharmaceutical Engineering session, Singapore-MIT Alliance Research Symposium, Singapore (2008)

  8. V. G. Yadav, "Receptor-mediated drug delivery: Insights & applications", Biochemical Engineering session, 1st AIChE-IIChE Joint Symposium, Mumbai, India (2004)


Poster Presentations



  1. S. H. Kamal, M. Kabiri, S. Hossain & V. G. Yadav, "Hydrogel formulations for ocular delivery", AIChE Conference, Minneapolis, USA (November 2017)

  2. A. Kritharis & V. G. Yadav, "Building a brain to develop cures for Alzheimer's disease", World Congress of Chemical Engineering, Barcelona, Spain (October 2017)

  3. M. Kabiri, S. H. Kamal, S. Pawar, P. Roy, S. Hossain & V. G. Yadav, "Medicine-by-design: Developing a cure for Epidermolysis Bullosa Simplex", World Congress of Chemical Engineering, Barcelona, Spain (October 2017)

  4. J. Varela & V. G. Yadav, "Constructing the mosquito olfactory pathway in bacteria", World Congress of Chemical Engineering, Barcelona, Spain (October 2017)

  5. A. Sharan, S. Hallam & V. G. Yadav, "Functional metagenomics towards the design of a cyclic bioprocess for valorizing pulp & paper mill sludge", AIChE Synthetic Biology, Engineering & Design Conference, Vancouver, BC (June 2017)

  6. J. C. H. Ho, S. Hallam & V. G. Yadav, "An improved whole-cell biosensor for the discovery of lignin-transforming enzymes in functional metagenomic screens", AIChE Synthetic Biology, Engineering & Design Conference, Vancouver, BC (June 2017)

  7. S. Ayakar, S. V. Pawar, S. J. Hallam and V. G. Yadav, "Multiplying productivity using metagenomics: Beyond canonical metabolic engineering", Synthetic Biology for Natural Products, Cancun, Mexico (March 2017)

  8. S. H. Kamal, M. Kabiri, S. Hossain & V. G. Yadav, "A stimulus-responsive, nanoparticle-laden polymeric formulation for ocular drug delivery", 2016 American Institute of Chemical Engineers Annual Meeting, San Francisco, CA (November 2016)

  9. C. Bayly & V. G. Yadav, "Carbon-to-fuel bioprocesses: Engineering biological systems for fuel production from captured carbon dioxide, COSIA Innovation Summit, Banff, AB (April 2015)

  10. C. Bayly & V. G. Yadav, "Enzyme Engineering for synthesis of next-generation biofuels, The University of British Columbia's Michael Smith Laboratories Research Summit, Vancouver, BC (August 2014)

  11. V. G. Yadav, S. Edgar & G. Stephanopoulos, "Rational enzyme redesign for enhancing activity and selectivity of heterologous taxane oxidation in engineered E. coli", Catalytic Mechanisms session, 2013 American Society for Biochemistry & Molecular Biology Conference on Experimental Biology, Boston, MA (2013)

  12. V. G. Yadav & G. Stephanopoulos, "Building better drugs using biosynthonics", GSK Global Chemistry Conference, Boston, MA (2013)

  13. V. G. Yadav, P. K. Ajikumar, C. G. Lim & G. Stephanopoulos, "Building better drugs", Massachusetts Life Sciences Innovation Day Symposium, Boston, MA (2012)

  14. V. G. Yadav, P. K. Ajikumar, C. G. Lim, S. Edgar & G. Stephanopoulos, "How to a build a superior drug", MIT Sloan BioInnovations Conference, Cambridge, MA (2012)

  15. V. G. Yadav, P. K. Ajikumar, C. G. Lim & G. Stephanopoulos, "Tuning the selectivity of a Taxus P450 monooxygenase", Current Topics in Biological Chemistry session, 243rd American Chemical Society National Meeting & Exposition, San Diego, CA (2012)

  16. V. G. Yadav, P. K. Ajikumar, C. G. Lim & G. Stephanopoulos, "Tuning the selectivity of a Taxus P450 monooxygenase", Frontiers in Biological Catalysis Conference, Cambridge, UK (2012)

  17. P. K. Ajikumar, V. G. Yadav & G. Stephanopoulos, "Systems biotechnology for mapping natural product pathways and their production in engineered microorganisms", Gordon Research Conference on Natural Products, New London, NH (2011)

  18. V. G. Yadav, P. K. Ajikumar & G. Stephanopoulos, "Systems biotechnology for drug discovery & development", MIT-ILP Systems Biology Conference, Cambridge, MA (2011)


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